Advanced oxidation protein products as a novel molecular basis of oxidative stress in uraemia

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Advanced oxidation protein products as a novel molecular basis of oxidative stress in uraemia.

status in chronic renal failure. Indeed, we described Oxidative stress in uraemia syndrome for the first time, the presence in the plasma of haemodialysed patients high levels of oxidized proteins that Considerable evidence has accumulated that chronic we designated AOPPs [11]. Since oxidative damage to uraemia is associated with a multifactorial immunoproteins modifies the spectroscopic charac...

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Advanced Oxidation Protein Products as a Novel Marker of Oxidative Stress in Postmenopausal Osteoporosis

BACKGROUND Advanced oxidation protein products (AOPPs) are acknowledged as a novel marker of oxidation-mediated protein damage. This study aimed to investigate the plasma levels of AOPPs in postmenopausal osteoporotic women, and to determine the relationship between AOPPs accumulation and lumbar bone mineral destiny (BMD) or bone turnover markers. MATERIAL AND METHODS Lumbar BMD was measured ...

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Advanced oxidation protein products as an oxidative stress marker in allergic rhinitis.

OBJECTIVES This study was designed to compare the levels of dityrosine-containing protein cross-link products, also known as advanced oxidation protein products (AOPP); in patients with allergic rhinitis with those in healthy individuals considering the fact that AOPP has the potential to be a marker of oxidative stress specific to proteins in mammalian systems. PATIENTS AND METHODS This stud...

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Advanced oxidation protein products: a causative link between oxidative stress and podocyte depletion.

Advanced oxidation protein products (AOPPs), a protein biomarker of increased oxidative stress, are elevated in uremic patients. Zhou et al. demonstrate that chronic administration of AOPPs induces podocyte apoptosis and proteinuria in normal rats via a cascade of signaling events. This study for the first time establishes a causative link between oxidative stress and podocyte depletion and cou...

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Advanced Oxidation Protein Products and Carbonylated Proteins as Biomarkers of Oxidative Stress in Selected Atherosclerosis-Mediated Diseases

OBJECTIVES The main question of this study was to evaluate the intensity of oxidative protein modification shown as advanced oxidation protein products (AOPP) and carbonylated proteins, expressed as protein carbonyl content (C=O) in abdominal aortic aneurysms (AAA), aortoiliac occlusive disease (AIOD), and chronic kidney disease (CKD). DESIGN AND METHODS The study was carried out in a group o...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 1999

ISSN: 1460-2385

DOI: 10.1093/ndt/14.suppl_1.76